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SkinBetter Science / treatment

InterFuse Intensive Treatment LINES dupes

~$245 Price not confirmed · 1 fl oz (30 ml); also 0.5 fl oz (15 ml)Save up to ~$213

Prices and listings checked Oct 28, 2026. Amazon prices change; the link shows today's price.

Official product page (opens in new tab)

How it works

A concentrated, no-needle 'filler-style' serum that delivers several sizes of hyaluronic acid (including injectable-grade HA and a sodium acetylated HA) in a silicone/ester vehicle, alongside a vitamin C ester and a set of peptides (acetyl hexapeptide-8, palmitoyl tripeptides, tetrapeptide-7). The HA plumps and hydrates the surface while peptides aim to soften expression lines.

  • Improves the appearance of deep expression lines and wrinkles
  • Injectable-grade hyaluronic acid delivered with InterFuse Technology plus four additional sizes of HA
  • A no-needle hyaluronic acid solution

Key actives

ActiveRoleAmount
Sodium Hyaluronate + Sodium Acetylated HyaluronateMulti-weight hyaluronic acid for hydration and plumpingundisclosed
Tetrahexyldecyl AscorbateStable vitamin C esterundisclosed
Acetyl Hexapeptide-8 (Argireline) and Hexapeptide-48 HClNeuro-calming peptides for expression linesundisclosed
Palmitoyl Tripeptide-1 / Palmitoyl Tetrapeptide-7Matrikine collagen-signalling peptidesundisclosed
Dipeptide Diaminobutyroyl Benzylamide DiacetateNeuro-calming peptideundisclosed
Acetyl Glucosamine, Glucosamine HCl, amino acidsHydration/skin-conditioningundisclosed

The dupes

Grouped by price tier; priced products first, then closest match.

budget Closest we found

The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)

The Ordinary

Match score 68 out of 100

No close match yet — we show the nearest formulas.

$32 · 1 fl oz (30 ml)Save ~$213

Shares

  • Acetyl hexapeptide-8
  • Palmitoyl tripeptide-1
  • Palmitoyl tetrapeptide-7
  • Dipeptide diaminobutyroyl benzylamide diacetate
  • Sodium hyaluronate crosspolymer + sodium hyaluronate

Misses

  • Vitamin C ester (THD ascorbate)
  • Injectable-grade HA delivery vehicle

Why it is close. This is the closest ingredient match: it contains four of LINES's five named peptides and two HA forms. It costs about $32 for 30 ml versus $245. The silicone-ester delivery vehicle is the main thing you lose.

Ingredient list source

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budget

The Ordinary Matrixyl 10% + HA

The Ordinary

Match score 55 out of 100
$10.90 · 1 fl oz (30 ml)Save ~$234.10

Shares

  • Palmitoyl tripeptide-1
  • Palmitoyl tetrapeptide-7
  • Sodium hyaluronate

Misses

  • Acetyl hexapeptide-8
  • Vitamin C ester
  • Additional HA weights

Why it is close. Two of LINES's peptides plus HA in one bottle at about $11.

Ingredient list source

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budget

The Ordinary Argireline Solution 10%

The Ordinary

Match score 50 out of 100
$9.70 · 1 fl oz (30 ml)Save ~$235.30

Shares

  • Acetyl hexapeptide-8 (Argireline, 10%)

Misses

  • Other peptides
  • Hyaluronic acid
  • Vitamin C ester

Why it is close. Argireline is a core active of LINES and is published at 10% here, which matches the expression-line goal. Pair with an HA serum.

Ingredient list source

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budget

The Ordinary Hyaluronic Acid 2% + B5 (with Ceramides)

The Ordinary

Match score 40 out of 100
$9.90 · 1 fl oz (30 ml)

Shares

  • Sodium hyaluronate (multiple molecular weights, including crosspolymer)
  • Panthenol

Misses

  • All peptides
  • Vitamin C ester

Why it is close. Covers the multi-weight hyaluronic acid hydration half, the part users feel immediately as plumping.

Ingredient list source

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Build it from parts

Argireline + Matrixyl + HA

$30.50Save $214.50

How to use. Patch test any new active on the inner forearm or behind the ear for 24-48 hours first. AM/PM on lines (forehead, between brows, crow's feet, smile lines): HA serum on damp skin, then Argireline, then Matrixyl, then moisturizer. Add vitamin C (Timeless) in the AM if you want the vitamin C piece. SPF 30+ daily. Results take 8-12 weeks.

Why it works. Rebuilds LINES's HA + hexapeptide-8 + palmitoyl-peptide profile with three $10 serums.

Multi-peptide serum + HA

$41.90Save $203.10

How to use. Patch test any new active on the inner forearm or behind the ear for 24-48 hours first. PM: HA serum on damp skin, then the peptide serum, then moisturizer. Keep copper peptides separate from L-ascorbic acid (use vitamin C in the morning only).

Why it works. Fewest steps: one dense peptide serum plus an HA serum.

What the science says

Full ingredient list

Show the INCI list

Water (Aqua), C12-15 Alkyl Benzoate, Glycerin, PEG-16 Macadamia Glycerides, Dimethicone, Acetyl Glucosamine, Alcohol Denat, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Citrate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Polyisobutene, Phenoxyethanol, Glycine Soja (Soybean) Seed Extract, Oleic Acid, Glucosamine Hcl, Ophiopogon Japonicus Root Extract, Pisum Sativum (Pea) Extract, Sorbitan Laurate, Citric Acid, Caprylyl Glycol, Bambusa Vulgaris Leaf/Stem Extract, PEG-7, Trimethylolpropane, Coconut, Sorbitan Isostearate, Hexylene Glycol, Acetylated Glycol Stearate, C18-36 Acid Glycol Ester, C18-36 Acid Triglyceride, Ethylhexylglycerin, Sodium Acetylated Hyaluronate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Hydrolyzed Lupine Protein, Glycine, Potassium Sorbate, Hydroxyproline, Carbomer, Hexapeptide-48 Hcl, Proline, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7

Source

Questions

What is the best dupe for InterFuse Intensive Treatment LINES?

The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%) by The Ordinary is our closest match at 68 out of 100 for $32 (1 fl oz (30 ml)). It shares Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Dipeptide diaminobutyroyl benzylamide diacetate, Sodium hyaluronate crosspolymer + sodium hyaluronate.

How much can I save on InterFuse Intensive Treatment LINES?

InterFuse Intensive Treatment LINES costs ~$245 for 1 fl oz (30 ml); also 0.5 fl oz (15 ml). The closest dupe costs $32, a saving of about $213. Prices change, so check the seller page.

Is The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%) exactly the same as InterFuse Intensive Treatment LINES?

No. Dupes share the key actives but can differ in concentration, vehicle and supporting ingredients. Missing from this one: Vitamin C ester (THD ascorbate), Injectable-grade HA delivery vehicle. See our methodology for how we score.

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