Niacinamide 10% + Zinc 1%
The Ordinary / 1 fl oz / $6
A cheap, well-tolerated niacinamide-zinc serum. The strength matches trial ranges, though 10% can sting some skin.
Buy on Amazon (opens in new tab)Concern
Uneven tone means patches of darker, redder or yellower skin from sun, past breakouts or irritation. Most people see gradual evening over 8-12 weeks, and a dermatologist should check any spot that is changing.
Reduces the transfer of pigment from pigment cells to skin cells. A trial showed it lowered hyperpigmentation and also reduced red blotchiness and sallowness over 12 weeks.
Inhibits an enzyme needed for pigment production and fights UV-driven oxidation. A systematic review found lightening effects, with long-term use needed.
Slows overactive pigment cells and calms inflammation. It matched 4% hydroquinone for melasma in a large trial.
Blocks visible light, which can darken pigment in medium-to-deep skin tones. Adding iron oxide improved melasma outcomes over UV-only sunscreen.
Cheapest first. Start with the budget pick.
The Ordinary / 1 fl oz / $6
A cheap, well-tolerated niacinamide-zinc serum. The strength matches trial ranges, though 10% can sting some skin.
Buy on Amazon (opens in new tab)Good Molecules / 1 oz / $10.77
Combines niacinamide with a tranexamic acid derivative for tone. Tranexamic acid evidence is still developing.
Buy on Amazon (opens in new tab)Timeless / 1 oz / $23.39
A 20% L-ascorbic acid with vitamin E and ferulic acid, the formula type with the best protective data. Store it cool and dark; it oxidizes.
Buy on Amazon (opens in new tab)CeraVe / 1.7 oz / ~$17
A tinted mineral SPF 30 containing iron oxides to cover visible light. Daily use keeps other tone treatments from being undone.
Buy on Amazon (opens in new tab)Paula's Choice / 0.67 oz / $53
A 10% niacinamide booster to add to any moisturizer. Stronger than most trial doses, so introduce slowly.
Buy on Amazon (opens in new tab)SkinCeuticals / 1 oz / ~$182
A 15% L-ascorbic acid formula studied in the lab for UV protection. Premium price for a formula you can approximate at lower cost.
Buy on Amazon (opens in new tab)Give any brightening product 8-12 weeks before judging it; sunscreen is non-negotiable.
Cautions. Patch test vitamin C, which can sting. Any new, dark or changing spot needs a dermatologist, not a serum.
This is general information, not medical advice. See a dermatologist for persistent or severe concerns.