IllustrationPart 1 · Good Molecules
Niacinamide Serum 10%
Niacinamide 10% serum (AM/PM)
Four steps: the original, what makes it special, the parts we use, and how to get closer.

SkinBetter Science
$225 · 1 fl oz (30 ml)
A non-retinoid serum built on plant-derived adaptogens (P.A.T.H.
Prices and listings checked Oct 28, 2026. Amazon prices change; the link shows today's price.
Evens tone, supports the barrier and helps with pores.
The Mystro antioxidant core that defines the formula beyond niacinamide.
No close retail equivalent: we credit at most 40% of these points.
Plant extracts aimed at calming stress-related redness and dullness.
No close retail equivalent: we credit at most 40% of these points.
A skin-like oil that softens and makes the serum feel cushiony.
Water-binding base.
Niacinamide + hydrating base
IllustrationPart 1 · Good Molecules
Niacinamide 10% serum (AM/PM)
IllustrationPart 2 · The Ordinary
Gentle lactic acid for dullness (PM, 1x/week)
IllustrationPart 3 · Paula's Choice
Adds: Alpha-lipoic acid, astaxanthin and ergothioneine antioxidant blend; Hyaluronic acid and glycerin
IllustrationPart 4 · The Ordinary
Adds: Squalane and light emollients
How to use. AM niacinamide; PM lactic acid once weekly on clean skin. Patch test. SPF 30+ every AM. Add Paula's Choice RESIST Ultra-Light Super Antioxidant Serum: Best antioxidant-plus-niacinamide mid-tier match; ingredient list and price not confirmed, so confidence is lower. Add The Ordinary 100% Plant-Derived Squalane: Plain squalane oil for the emollient part; check the current product page for size and price.
Partial credit means the part only partly matches that standout.
The total leaves out the 2 parts showing "Check price".
57 / 100. One add-on lifts this build to 62/100.
IllustrationThe Ordinary
+5 pts → 62/100 · +$9.90
Cheap hyaluronic acid serum for the humectant part of the formula.
70 is our ceiling. No retail serum pairs alpha-lipoic acid, astaxanthin and ergothioneine; other antioxidant serums give partial credit. This botanical set has no retail match; nothing at retail covers it.
One bottle instead of a build. Sorted by match score; scores use the same standouts as above.
Paula's Choice
No close match yet — we show the nearest formulas.
Why it is close. Best antioxidant-plus-niacinamide mid-tier match; ingredient list and price not confirmed, so confidence is lower.
CeraVe
Why it is close. Barrier and niacinamide support only; includes retinol, which Mystro does not have.
Good Molecules
Why it is close. Another high-percentage niacinamide serum; same limited overlap. Price approximate.
The Ordinary
Why it is close. Niacinamide is the only shared active at a very low price; Mystro's antioxidant and adaptogen blend has no budget equivalent.
The INKEY List
Why it is close. Niacinamide serum. Price not found.
Topical niacinamide (5%, 12 weeks, split-face) improved fine lines, hyperpigmented spots, redness and sallowness in aging facial skin.
Bissett 2005 · Dermatol SurgA 5% alpha-lipoic acid cream was tested in a randomized, placebo-controlled, double-blind study on photoaged facial skin.
Beitner 2003 · Br J DermatolAqua/Water, Copaifera Officinalis (Balsam Copaiba) Resin, Glycerin, Butylene Glycol, Propanediol, Polyglyceryl-3 Distearate, Isosorbide Dicaprylate, Cetearyl Glucoside, Ethoxydiglycol, Diheptyl Succinate, Squalane, Niacinamide, Panax Notoginseng Root Extract, Theobroma Cacao (Cocoa) Leaf Cell Extract, Chamomilla Recutita (Matricaria) Flower Extract, Magnolia Officinalis Bark Extract, Echinacea Purpurea Extract, Sophora Japonica Bud Extract, Humulus Lupulus (Hops) Extract, Curcuma Longa (Turmeric) Root Extract, Hydrolyzed Sodium Hyaluronate, Haematococcus Pluvialis Extract, Astaxanthin, Ergothioneine, Thioctic Acid, Sorbitan Olivate, Tocopherol, Caprylic/Capric Triglyceride, Capryloyl Glycerin/Sebacic Acid Copolymer, Sodium Stearoyl Glutamate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Glyceryl Stearate Citrate, Tribehenin, Cetearyl Alcohol, Acacia Senegal Gum, Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Phenethyl Alcohol, Phenoxyethanol, Citric Acid, Phytic Acid, Sodium Hydroxide
We split Mystro Active Balance Serum into 5 standout parts worth 100 points in total. The build earns 57 of a possible 70. 70 is the most we claim, because some standouts have no close retail equivalent.
RESIST Ultra-Light Super Antioxidant Serum by Paula's Choice is our closest single-product match at 32 out of 100 (1 oz). It shares Antioxidants (CoQ10, niacinamide, hyaluronic acid per Paula's description).
Mystro Active Balance Serum costs $225 for 1 fl oz (30 ml). The closest dupe has no price we could confirm (see the seller page). Prices change, so check the seller page.
No. Dupes share the key actives but can differ in concentration, vehicle and supporting ingredients. Missing from this one: Alpha lipoic acid, Astaxanthin, Ergothioneine, Botanical adaptogens. See our methodology for how we score.