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How we build InterFuse Treatment Cream EYE

The original, what makes it special, the shelf parts we use and how to get closer. Add or swap parts and the score updates.

InterFuse Treatment Cream EYE

The original · SkinBetter Science

InterFuse Treatment Cream EYE

~$135 Price not confirmed · 0.5 fl oz (15 ml)

An eye cream that combines niacinamide, caffeine, Kakadu plum (natural vitamin C) and several peptides (including palmitoyl tripeptide-38 and a conotoxin-like peptide) with hyaluronic acid.

Official product page (opens in new tab)

Prices and listings checked Oct 28, 2026. Amazon prices change; the link shows today's price.

Step 2 · The build

Our build 4 parts

Caffeine serum + niacinamide eye routine

  • Illustration of The Ordinary Caffeine Solution 5% + EGCG

    The Ordinary

    The Ordinary Caffeine Solution 5% + EGCG

    Depuffing caffeine serum

    DCaffeine · 20FSodium hyaluronate · 5 of 10
    $9.20Buy on Amazon (opens in new tab)
  • Illustration of The Ordinary Niacinamide 10% + Zinc 1%

    The Ordinary

    The Ordinary Niacinamide 10% + Zinc 1%

    Niacinamide (use a pea-sized amount on orbital bone, not on the lid)

    ANiacinamide · 25
    ~$6Buy on Amazon (opens in new tab)
  • Illustration of The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)

    The Ordinary

    The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)

    Adds: Palmitoyl tripeptide-38; Conotoxin-like peptide and copper peptide; Sodium hyaluronate

    BPalmitoyl tripeptide-38 · 15 of 20CConotoxin-like peptide and copper peptide · 4 of 15FSodium hyaluronate · 8 of 10
    $32Buy on Amazon (opens in new tab)
  • Illustration of Timeless Skin Care Timeless 20% Vitamin C + E Ferulic Acid Serum

    Timeless Skin Care

    Timeless Skin Care Timeless 20% Vitamin C + E Ferulic Acid Serum

    Adds: Kakadu plum (natural vitamin C)

    EKakadu plum (natural vitamin C) · 8 of 10
    $27.95Buy on Amazon (opens in new tab)

Partial credit means the part only partly matches that standout.

The 100 points

What stands out 100 pts

We split InterFuse Treatment Cream EYE into 6 standout parts. Each bar shows what the build earns.

  • ANiacinamide25 of 25 pts

    Brightens tone and strengthens the barrier; it sits high in the ingredient list.

    Bissett 2005 · Dermatol Surg
  • BPalmitoyl tripeptide-3815 of 20 pts

    A signal peptide aimed at crow's feet and crepiness.

  • CConotoxin-like peptide and copper peptide4 of 15 pts

    A smoothing peptide pair for expression lines.

    No close retail equivalent: we credit at most 25% of these points.

  • DCaffeine20 of 20 pts

    Helps with puffiness and dark circles.

    Herman 2013 · Skin Pharmacol Physiol
  • EKakadu plum (natural vitamin C)8 of 10 pts

    A natural vitamin C source for brightening.

    Lintner 2020 · J Cosmet Dermatol
  • FSodium hyaluronate8 of 10 pts

    Hydrates and plumps.

    Pavicic 2011 · J Drugs Dermatol

Optional

Get closer optional

80 / 100. One add-on lifts this build to 82/100.

Illustration of The Ordinary Hyaluronic Acid 2% + B5 (with Ceramides)Illustration

Add The Ordinary Hyaluronic Acid 2% + B5 (with Ceramides)

The Ordinary

+2 pts → 82/100 · +$9.90

FSodium hyaluronate · +2

Plain hyaluronic acid layer for full hydration credit.

$9.90Buy on Amazon (opens in new tab)

84 is our ceiling. Retail products use it at an unknown dose. The conotoxin-like peptide is proprietary; copper peptides give only trace credit. With the add-on the build costs ~$85.05.

Step 3 · Buy

Buy the build

One link per part. Each opens the retailer in a new tab.

Skincare SuppliesOct 28, 2026

Your build

  1. 01The OrdinaryThe Ordinary Caffeine Solution 5% + EGCG$9.20

    Running total $9.20

    Buy on Amazon (opens in new tab)
  2. 02The OrdinaryThe Ordinary Niacinamide 10% + Zinc 1%~$6

    Running total ~$15.20

    Buy on Amazon (opens in new tab)
  3. 03The OrdinaryThe Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)$32

    Running total ~$47.20

    Buy on Amazon (opens in new tab)
  4. 04Timeless Skin CareTimeless Skin Care Timeless 20% Vitamin C + E Ferulic Acid Serum$27.95

    Running total ~$75.15

    Buy on Amazon (opens in new tab)
Build total~$75.15
The splurge~$135
Match80/100
You keep~$59.85

Snapshot prices. Each link shows today's price.

How to use

  1. Patch test any new active on the inner forearm or behind the ear for 24-48 hours first. AM/PM: tap caffeine serum on the orbital bone, then niacinamide, then a plain eye cream or moisturizer. Keep niacinamide away from the lash line if it stings.
  2. Add The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%): It lists the same palmitoyl tripeptide-38 and a copper peptide, so it matches InterFuse EYE's peptide set best. Serum format; safe near eyes per label but patch test.
  3. Add Timeless Skin Care Timeless 20% Vitamin C + E Ferulic Acid Serum: A stronger vitamin C than Kakadu plum; keep it off the eyelid.

Other single-product swaps

One bottle instead of a build. Sorted by match score; scores use the same standouts as above.

budget Closest we found

Minimalist Caffeine Eye Cream with Vitamin K, Retinal and Peptides

Minimalist

Match score 56 out of 100

No close match yet — we show the nearest formulas.

Check price on Amazon · 14 g / 0.49 oz
What it shares, what it misses

Shares

  • Niacinamide
  • Caffeine
  • Hydrolyzed Sodium Hyaluronate + Sodium Hyaluronate
  • Palmitoyl Tripeptide-1 / Palmitoyl Tetrapeptide-7 (Matrixyl 3000)

Misses

  • Palmitoyl Tripeptide-38
  • s-Mu-conotoxin / copper peptides
  • Kakadu plum

Why it is close. Niacinamide is 3rd and caffeine 6th on the list, with Matrixyl 3000 peptides and two forms of hyaluronate; it also adds 0.1% retinal.

Buy on Amazon (opens in new tab)
budget

Olay Brightening Eye Cream with Vitamin C (Vitamin C + Peptide 24 Eye Cream)

Olay

Match score 29 out of 100
~$29.99 Price not confirmed · 0.5 oz
What it shares, what it misses

Shares

  • Niacinamide
  • Vitamin C
  • Peptides

Misses

  • Caffeine (not confirmed)
  • Palmitoyl tripeptide-38
  • Conotoxin-like peptide

Why it is close. Brightening eye cream built on vitamin C, niacinamide and peptides, the same brightening side of InterFuse EYE. Full INCI not retrieved; actives from Olay's own marketing.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)

The Ordinary

Match score 27 out of 100
$32 · 1 fl oz (30 ml)
What it shares, what it misses

Shares

  • Palmitoyl tripeptide-38
  • Palmitoyl tripeptide-1
  • Palmitoyl tetrapeptide-7
  • Copper tripeptide-1
  • Acetyl hexapeptide-8
  • Sodium hyaluronate

Misses

  • Niacinamide
  • Caffeine
  • Kakadu plum

Why it is close. It lists the same palmitoyl tripeptide-38 and a copper peptide, so it matches InterFuse EYE's peptide set best. Serum format; safe near eyes per label but patch test.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

The Ordinary Caffeine Solution 5% + EGCG

The Ordinary

Match score 25 out of 100
$9.20 · 1 fl oz (30 ml)
What it shares, what it misses

Shares

  • Caffeine (5%)
  • EGCG-type antioxidant (epigallocatechin gallatyl glucoside)
  • Hyaluronic acid

Misses

  • Niacinamide
  • Peptides
  • Vitamin C
  • Moisturizing cream base

Why it is close. Strong caffeine dose for puffiness and dark circles at a tenth of the price. A watery serum, so it needs a cream over it.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

The INKEY List Caffeine Eye Cream

The INKEY List

Match score 20 out of 100
Check price on Amazon · 0.5 fl oz (15 ml)
What it shares, what it misses

Shares

  • Caffeine
  • Matrixyl-family peptides (palmitoyl tripeptide-1, tetrapeptide-7)
  • Hyaluronic acid
  • Jojoba esters

Misses

  • Niacinamide
  • Palmitoyl tripeptide-38
  • Kakadu plum / vitamin C

Why it is close. Cream that pairs caffeine with the palmitoyl peptides and hyaluronic acid, hitting the depuffing and fine-line sides of InterFuse EYE. No niacinamide.

Ingredient list source

Buy on Amazon (opens in new tab)

What the science says

  • Caffeine is widely used in cosmetics for antioxidant, microcirculation and photoaging-protective effects; topical products typically contain about 3% caffeine.

    Herman 2013 · Skin Pharmacol Physiol

  • A serum with 15% L-ascorbic acid, vitamin E and palmitoyl tripeptide-38 improved skin roughness, redness and homogeneity in 56 days.

    Lintner 2020 · J Cosmet Dermatol

  • Topical hyaluronic acid (0.1%) improved periocular hydration, elasticity and wrinkle depth versus vehicle in a randomized trial.

    Pavicic 2011 · J Drugs Dermatol

Full ingredient list

Show the INCI list

Aqua/Water, Caprylyl Methicone, Glycerin, Jojoba Esters, Niacinamide, PEG-16 Macadamia Glycerides, Cetearyl Alcohol, Glyceryl Stearate, Ceteareth-20, PEG-100 Stearate, Caprylic/Capric Triglyceride, Alcohol Denat., Palmitoyl Tripeptide-38, Caffeine, s-Mu-conotoxin CnIIIC Acetate, Copper Lysinate/Prolinate, Hydrolyzed Lupine Protein, Terminalia Ferdinandiana Fruit Extract, Methylglucoside Phosphate, Sodium Hyaluronate, Saccharomyces Cerevisiae Extract, Arginine, Glycine, Hydroxypropyl Cyclodextrin, Carbomer, Hexylene Glycol, Citric Acid, Sodium Hydroxide, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol

Source

Questions

What does the 80/100 score for our InterFuse Treatment Cream EYE build mean?

We split InterFuse Treatment Cream EYE into 6 standout parts worth 100 points in total. The build earns 80 of a possible 84. 84 is the most we claim, because some standouts have no close retail equivalent.

What is the best dupe for InterFuse Treatment Cream EYE?

Minimalist Caffeine Eye Cream with Vitamin K, Retinal and Peptides by Minimalist is our closest single-product match at 56 out of 100 (14 g / 0.49 oz). It shares Niacinamide, Caffeine, Hydrolyzed Sodium Hyaluronate + Sodium Hyaluronate, Palmitoyl Tripeptide-1 / Palmitoyl Tetrapeptide-7 (Matrixyl 3000).

How much can I save on InterFuse Treatment Cream EYE?

InterFuse Treatment Cream EYE costs ~$135 for 0.5 fl oz (15 ml). The closest dupe has no price we could confirm (see the seller page). Prices change, so check the seller page.

Is Minimalist Caffeine Eye Cream with Vitamin K, Retinal and Peptides exactly the same as InterFuse Treatment Cream EYE?

No. Dupes share the key actives but can differ in concentration, vehicle and supporting ingredients. Missing from this one: Palmitoyl Tripeptide-38, s-Mu-conotoxin / copper peptides, Kakadu plum. See our methodology for how we score.

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