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How we build AlphaRet Overnight Cream

The original, what makes it special, the shelf parts we use and how to get closer. Add or swap parts and the score updates.

AlphaRet Overnight Cream

The original · SkinBetter Science

AlphaRet Overnight Cream

$145 · 1 fl oz (30 ml)

A retinoid (ethyl lactyl retinoate) is chemically bonded to lactic acid, so it is said to act as retinoid and AHA together with less irritation than separate retinol.

Official product page (opens in new tab)

Prices and listings checked Oct 28, 2026. Amazon prices change; the link shows today's price.

Step 2 · The build

Our build 4 parts

Retinol serum + lactic acid, alternating nights

  • Illustration of CeraVe Resurfacing Retinol Serum

    CeraVe

    Resurfacing Retinol Serum

    Retinoid + niacinamide + ceramides (PM, retinoid nights)

    AAlphaRet retinoid-lactic conjugate · 14 of 35ENiacinamide · 8 of 10FCeramide NP, hyaluronic acid and CoQ10 · 5 of 10
    $21.99Buy on Amazon (opens in new tab)
  • Illustration of The Ordinary Lactic Acid 10% + HA

    The Ordinary

    Lactic Acid 10% + HA

    AHA exfoliant (PM, alternate nights)

    BGlycolic acid · 8 of 15
    $9.20Buy on Amazon (opens in new tab)
  • Illustration of Paula's Choice CLINICAL 1% Retinol Treatment

    Paula's Choice

    CLINICAL 1% Retinol Treatment

    Adds: Tetrahexyldecyl ascorbate (oil-soluble vitamin C); Palmitoyl tripeptide-1 and tetrapeptide-7

    AAlphaRet retinoid-lactic conjugate · 14 of 35CTetrahexyldecyl ascorbate (oil-soluble vitamin C) · 11 of 15DPalmitoyl tripeptide-1 and tetrapeptide-7 · 11 of 15
    ~$65Buy on Amazon (opens in new tab)
  • Illustration of Minimalist Multi Peptide + Hyaluronic Acid Serum

    Minimalist

    Minimalist Multi Peptide + Hyaluronic Acid Serum

    Adds: Palmitoyl tripeptide-1 and tetrapeptide-7

    DPalmitoyl tripeptide-1 and tetrapeptide-7 · 15FCeramide NP, hyaluronic acid and CoQ10 · 3 of 10
    ~$12.99Buy on Amazon (opens in new tab)

    Listing not re-checked. Check the title and size on the retailer page.

Partial credit means the part only partly matches that standout.

The 100 points

What stands out 100 pts

We split AlphaRet Overnight Cream into 6 standout parts. Each bar shows what the build earns.

  • AAlphaRet retinoid-lactic conjugate14 of 35 pts

    The defining active: a retinoid bonded to lactic acid, meant to work as retinoid and AHA together with less irritation.

    No close retail equivalent: we credit at most 40% of these points.

    McDaniel 2017 · J Cosmet DermatolGrimes 2024 · J Cosmet Dermatol
  • BGlycolic acid8 of 15 pts

    Exfoliates the surface for smoother texture and a brighter look.

    Sharad 2013 · Clin Cosmet Investig Dermat…
  • CTetrahexyldecyl ascorbate (oil-soluble vitamin C)11 of 15 pts

    A stable vitamin C form that helps with uneven tone and dullness.

  • DPalmitoyl tripeptide-1 and tetrapeptide-715 of 15 pts

    Signal peptides aimed at lines and firmness.

    Robinson 2005 · Int J Cosmet Sci
  • ENiacinamide8 of 10 pts

    Supports barrier and even-looking tone.

    Bissett 2005 · Dermatol Surg
  • FCeramide NP, hyaluronic acid and CoQ105 of 10 pts

    Barrier lipids, hydration and an antioxidant that make a strong retinoid easier to tolerate.

Optional

Get closer score under 80

61 / 100. One add-on lifts this build to 64/100.

Illustration of The Ordinary Glycolic Acid 7% Exfoliating TonerIllustration

Add The Ordinary Glycolic Acid 7% Exfoliating Toner

The Ordinary

+3 pts → 64/100 · +$9

BGlycolic acid · +3

Adds a dedicated glycolic step on a separate night.

$9Buy on Amazon (opens in new tab)

79 is our ceiling. Proprietary conjugate: no retail product uses ethyl lactyl retinoate. Retinol or HPR retinoids give partial credit only. With the add-on the build costs ~$118.18.

Step 3 · Buy

Buy the build

One link per part. Each opens the retailer in a new tab.

Skincare SuppliesOct 28, 2026

Your build

  1. 01CeraVeResurfacing Retinol Serum$21.99

    Running total $21.99

    Buy on Amazon (opens in new tab)
  2. 02The OrdinaryLactic Acid 10% + HA$9.20

    Running total $31.19

    Buy on Amazon (opens in new tab)
  3. 03Paula's ChoiceCLINICAL 1% Retinol Treatment~$65

    Running total ~$96.19

    Buy on Amazon (opens in new tab)

    Cheaper generic: The Ordinary Retinol 1% in Squalane (opens in new tab) at Amazon, $15.94 for 1 fl oz (30 ml). ~$15.94/fl oz vs ~$65/fl oz, about 75% less per fl oz. Snapshot prices dated Oct 28, 2026. A different product, a close match, not identical; ingredient source (opens in new tab). Affiliate link.

    Cheaper in store: Retinol Night Serum. In store at Trader Joe's, $9.99 (price as of Oct 28, 2026), no link, we don't earn from this. 1 fl oz. ~$9.99/fl oz vs ~$65/fl oz, about 85% less per fl oz. A different product, a close match, not identical. Concentration not stated. The ingredient list comes from a third party, so check the label in store: ingredient source (opens in new tab).

  4. 04MinimalistMinimalist Multi Peptide + Hyaluronic Acid Serum~$12.99

    Running total ~$109.18

    Buy on Amazon (opens in new tab)

    Listing not re-checked. Check the title and size on the retailer page.

Build total~$109.18
The splurge$145
Match61/100
You keep~$35.82

Snapshot prices. Each link shows today's price.

How to use

  1. PM only. Cleanse, apply retinol serum on retinoid nights (start 2 nights/week); on the other nights use lactic acid 10% 1-2 times/week instead, never layered the same night. Patch test behind the ear for 48 hours first. Use SPF 30+ every AM.
  2. Add Paula's Choice CLINICAL 1% Retinol Treatment: Mid-tier option with retinol, peptides and THD ascorbate, matching the vitamin C and peptide side of AlphaRet. Costs less than half as much.
  3. Add Minimalist Multi Peptide + Hyaluronic Acid Serum: Same Matrixyl 3000 peptide pair as the original, high on the list; a peptide add-on, not a retinoid swap.

Other single-product swaps

One bottle instead of a build. Sorted by match score; scores use the same standouts as above.

mid Closest we found

CLINICAL 1% Retinol Treatment

Paula's Choice

Match score 36 out of 100

No close match yet — we show the nearest formulas.

~$65 Price not confirmed · 1 fl oz
What it shares, what it misses

Shares

  • Retinol
  • Peptides
  • THD ascorbate (vitamin C)
  • Licorice

Misses

  • AHA
  • Ethyl lactyl retinoate

Why it is close. Mid-tier option with retinol, peptides and THD ascorbate, matching the vitamin C and peptide side of AlphaRet. Costs less than half as much.

Ingredient list source

Buy on Amazon (opens in new tab)

Cheaper generic: The Ordinary Retinol 1% in Squalane (opens in new tab) at Amazon, $15.94 for 1 fl oz (30 ml). ~$15.94/fl oz vs ~$65/fl oz, about 75% less per fl oz. Snapshot prices dated Oct 28, 2026. A different product, a close match, not identical; ingredient source (opens in new tab). Affiliate link.

Cheaper in store: Retinol Night Serum. In store at Trader Joe's, $9.99 (price as of Oct 28, 2026), no link, we don't earn from this. 1 fl oz. ~$9.99/fl oz vs ~$65/fl oz, about 85% less per fl oz. A different product, a close match, not identical. Concentration not stated. The ingredient list comes from a third party, so check the label in store: ingredient source (opens in new tab).

budget

Retinol 24 MAX Night Moisturizer

Olay

Match score 30 out of 100
~$34.99 Price not confirmed · 1.7 oz
What it shares, what it misses

Shares

  • Retinol
  • Niacinamide
  • Peptides

Misses

  • AHA
  • Ethyl lactyl retinoate
  • Ceramides

Why it is close. Retinol plus niacinamide and a peptide in a moisturizing base. No exfoliating acid, so add one separately.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

Resurfacing Retinol Serum

CeraVe

Match score 27 out of 100
$21.99 · 1 fl oz
What it shares, what it misses

Shares

  • Retinol (retinoid)
  • Niacinamide
  • Ceramides
  • Hyaluronic acid

Misses

  • AHA bonded to retinoid
  • Glycolic acid
  • Vitamin C (THD ascorbate)
  • Peptides

Why it is close. Closest budget serum: a true retinoid plus niacinamide and ceramides at about 15 percent of the price. It lacks the AHA component, so pair it with a lactic or glycolic step. Ethyl lactyl retinoate (AlphaRet) is proprietary and not sold in any dupe, so every match is a functional approximation.

Ingredient list source

Buy on Amazon (opens in new tab)

Cheaper in store: Retinol Night Serum. In store at Trader Joe's, $9.99 (price as of Oct 28, 2026), no link, we don't earn from this. 1 fl oz. $9.99/fl oz vs $21.99/fl oz, about 55% less per fl oz. A different product, a close match, not identical. Concentration not stated. The ingredient list comes from a third party, so check the label in store: ingredient source (opens in new tab).

budget

Retinol Correxion Deep Wrinkle Night Cream

RoC

Match score 26 out of 100
~$21.99 Price not confirmed · 1 oz
What it shares, what it misses

Shares

  • Retinol
  • Glycolic acid
  • Vitamin C

Misses

  • Ethyl lactyl retinoate
  • Ceramides
  • Peptides
  • CoQ10

Why it is close. A night cream that also combines retinol, glycolic acid and vitamin C, the nearest active mix at drugstore price. Texture is heavier and irritation risk is likely higher than AlphaRet.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

Minimalist Retinal 0.2% Liposomal Cream

Minimalist

Match score 19 out of 100
Check price on Amazon · 20 g / 0.7 oz
What it shares, what it misses

Shares

  • Retinal
  • Hydrolyzed sodium hyaluronate
  • Resveratrol

Misses

  • Glycolic acid
  • THD ascorbate
  • Niacinamide
  • Peptides
  • Ceramide NP

Why it is close. Publishes 0.2% retinal (a stronger retinoid than retinol) in a simple cream with resveratrol and EUK-134; no other AlphaRet actives.

Buy on Amazon (opens in new tab)
budget

Minimalist Multi Peptide + Hyaluronic Acid Serum

Minimalist

Match score 18 out of 100
~$12.99 Price not confirmed · 30 ml / 1 fl oz
What it shares, what it misses

Shares

  • Palmitoyl tripeptide-1
  • Palmitoyl tetrapeptide-7
  • Sodium hyaluronate

Misses

  • Retinoid
  • Glycolic acid
  • Tetrahexyldecyl ascorbate
  • Niacinamide
  • Ceramide NP

Why it is close. Same Matrixyl 3000 peptide pair as the original, high on the list; a peptide add-on, not a retinoid swap.

Ingredient list source

Listing not re-checked. Check the product title and size on the retailer page.

Buy on Amazon (opens in new tab)
budget

Granactive Retinoid 2% Emulsion

The Ordinary

Match score 14 out of 100
~$12.10 Price not confirmed · 30 ml
What it shares, what it misses

Shares

  • Retinoid (HPR plus retinol blend)

Misses

  • AHA
  • Niacinamide
  • Peptides
  • Ceramides

Why it is close. Cheapest way to get an ester-type retinoid. Low-irritation HPR is the nearest chemical cousin, but it has no AHA or supporting actives.

Ingredient list source

Buy on Amazon (opens in new tab)

What the science says

Full ingredient list

Show the INCI list

Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891)

Source

Questions

What does the 61/100 score for our AlphaRet Overnight Cream build mean?

We split AlphaRet Overnight Cream into 6 standout parts worth 100 points in total. The build earns 61 of a possible 79. 79 is the most we claim, because some standouts have no close retail equivalent.

What is the best dupe for AlphaRet Overnight Cream?

CLINICAL 1% Retinol Treatment by Paula's Choice is our closest single-product match at 36 out of 100 for ~$65 (1 fl oz). It shares Retinol, Peptides, THD ascorbate (vitamin C), Licorice.

How much can I save on AlphaRet Overnight Cream?

AlphaRet Overnight Cream costs $145 for 1 fl oz (30 ml). The closest dupe costs ~$65, a saving of about $80. Prices change, so check the seller page.

Is CLINICAL 1% Retinol Treatment exactly the same as AlphaRet Overnight Cream?

No. Dupes share the key actives but can differ in concentration, vehicle and supporting ingredients. Missing from this one: AHA, Ethyl lactyl retinoate. See our methodology for how we score.

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