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How we build InterFuse Treatment Cream EYE

Four steps: the original, what makes it special, the parts we use, and how to get closer.

The original

InterFuse Treatment Cream EYE

SkinBetter Science

InterFuse Treatment Cream EYE

~$135 Price not confirmed · 0.5 fl oz (15 ml)

An eye cream that combines niacinamide, caffeine, Kakadu plum (natural vitamin C) and several peptides (including palmitoyl tripeptide-38 and a conotoxin-like peptide) with hyaluronic acid.

Official product page (opens in new tab)

Prices and listings checked Oct 28, 2026. Amazon prices change; the link shows today's price.

What stands out 100 pts

  • ANiacinamide25 pts

    Brightens tone and strengthens the barrier; it sits high in the ingredient list.

  • BPalmitoyl tripeptide-3820 pts

    A signal peptide aimed at crow's feet and crepiness.

  • CConotoxin-like peptide and copper peptide15 pts

    A smoothing peptide pair for expression lines.

    No close retail equivalent: we credit at most 25% of these points.

  • DCaffeine20 pts

    Helps with puffiness and dark circles.

  • EKakadu plum (natural vitamin C)10 pts

    A natural vitamin C source for brightening.

  • FSodium hyaluronate10 pts

    Hydrates and plumps.

Total to match100 pts
Now we cover those 6 with shelf products

Our build 4 parts

Caffeine serum + niacinamide eye routine

Illustration of The Ordinary Caffeine Solution 5% + EGCGIllustration

Part 1 · The Ordinary

The Ordinary Caffeine Solution 5% + EGCG

Depuffing caffeine serum

DCaffeine · 20FSodium hyaluronate · 5 of 10
Illustration of The Ordinary Niacinamide 10% + Zinc 1%Illustration

Part 2 · The Ordinary

The Ordinary Niacinamide 10% + Zinc 1%

Niacinamide (use a pea-sized amount on orbital bone, not on the lid)

ANiacinamide · 25
Illustration of The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)Illustration

Part 3 · The Ordinary

The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)

Adds: Palmitoyl tripeptide-38; Conotoxin-like peptide and copper peptide; Sodium hyaluronate

BPalmitoyl tripeptide-38 · 15 of 20CConotoxin-like peptide and copper peptide · 4 of 15FSodium hyaluronate · 8 of 10
Illustration of Timeless Skin Care Timeless 20% Vitamin C + E Ferulic Acid SerumIllustration

Part 4 · Timeless Skin Care

Timeless Skin Care Timeless 20% Vitamin C + E Ferulic Acid Serum

Adds: Kakadu plum (natural vitamin C)

EKakadu plum (natural vitamin C) · 8 of 10

How to use. Patch test any new active on the inner forearm or behind the ear for 24-48 hours first. AM/PM: tap caffeine serum on the orbital bone, then niacinamide, then a plain eye cream or moisturizer. Keep niacinamide away from the lash line if it stings. Add The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%): It lists the same palmitoyl tripeptide-38 and a copper peptide, so it matches InterFuse EYE's peptide set best. Serum format; safe near eyes per label but patch test. Add Timeless Skin Care Timeless 20% Vitamin C + E Ferulic Acid Serum: A stronger vitamin C than Kakadu plum; keep it off the eyelid.

Partial credit means the part only partly matches that standout.

Match score80 / 100
  • A · D fully covered45 pts
  • B · C · E · F partly covered35 pts
InterFuse Treatment Cream EYE~$135
Our build$75.15
You save~$59.85

Get closer optional

80 / 100. One add-on lifts this build to 82/100.

Illustration of The Ordinary Hyaluronic Acid 2% + B5 (with Ceramides)Illustration

Add The Ordinary Hyaluronic Acid 2% + B5 (with Ceramides)

The Ordinary

+2 pts → 82/100 · +$9.90

FSodium hyaluronate · +2

Plain hyaluronic acid layer for full hydration credit.

84 is our ceiling. Retail products use it at an unknown dose. The conotoxin-like peptide is proprietary; copper peptides give only trace credit. With the add-on the build costs ~$85.05.

Other single-product swaps

One bottle instead of a build. Sorted by match score; scores use the same standouts as above.

budget Closest we found

Olay Brightening Eye Cream with Vitamin C (Vitamin C + Peptide 24 Eye Cream)

Olay

Match score 29 out of 100

No close match yet — we show the nearest formulas.

~$29.99 Price not confirmed · 0.5 oz
What it shares, what it misses

Shares

  • Niacinamide
  • Vitamin C
  • Peptides

Misses

  • Caffeine (not confirmed)
  • Palmitoyl tripeptide-38
  • Conotoxin-like peptide

Why it is close. Brightening eye cream built on vitamin C, niacinamide and peptides, the same brightening side of InterFuse EYE. Full INCI not retrieved; actives from Olay's own marketing.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

The Ordinary "Buffet" + Copper Peptides 1% (now sold as Multi-Peptide + Copper Peptides 1%)

The Ordinary

Match score 27 out of 100
$32 · 1 fl oz (30 ml)
What it shares, what it misses

Shares

  • Palmitoyl tripeptide-38
  • Palmitoyl tripeptide-1
  • Palmitoyl tetrapeptide-7
  • Copper tripeptide-1
  • Acetyl hexapeptide-8
  • Sodium hyaluronate

Misses

  • Niacinamide
  • Caffeine
  • Kakadu plum

Why it is close. It lists the same palmitoyl tripeptide-38 and a copper peptide, so it matches InterFuse EYE's peptide set best. Serum format; safe near eyes per label but patch test.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

The Ordinary Caffeine Solution 5% + EGCG

The Ordinary

Match score 25 out of 100
$9.20 · 1 fl oz (30 ml)
What it shares, what it misses

Shares

  • Caffeine (5%)
  • EGCG-type antioxidant (epigallocatechin gallatyl glucoside)
  • Hyaluronic acid

Misses

  • Niacinamide
  • Peptides
  • Vitamin C
  • Moisturizing cream base

Why it is close. Strong caffeine dose for puffiness and dark circles at a tenth of the price. A watery serum, so it needs a cream over it.

Ingredient list source

Buy on Amazon (opens in new tab)
budget

The INKEY List Caffeine Eye Cream

The INKEY List

Match score 20 out of 100
Check price on Amazon · 0.5 fl oz (15 ml)
What it shares, what it misses

Shares

  • Caffeine
  • Matrixyl-family peptides (palmitoyl tripeptide-1, tetrapeptide-7)
  • Hyaluronic acid
  • Jojoba esters

Misses

  • Niacinamide
  • Palmitoyl tripeptide-38
  • Kakadu plum / vitamin C

Why it is close. Cream that pairs caffeine with the palmitoyl peptides and hyaluronic acid, hitting the depuffing and fine-line sides of InterFuse EYE. No niacinamide.

Ingredient list source

Buy on Amazon (opens in new tab)

What the science says

  • Caffeine is widely used in cosmetics for antioxidant, microcirculation and photoaging-protective effects; topical products typically contain about 3% caffeine.

    Herman 2013 · Skin Pharmacol Physiol
  • A serum with 15% L-ascorbic acid, vitamin E and palmitoyl tripeptide-38 improved skin roughness, redness and homogeneity in 56 days.

    Lintner 2020 · J Cosmet Dermatol
  • Topical hyaluronic acid (0.1%) improved periocular hydration, elasticity and wrinkle depth versus vehicle in a randomized trial.

    Pavicic 2011 · J Drugs Dermatol

Full ingredient list

Show the INCI list

Aqua/Water, Caprylyl Methicone, Glycerin, Jojoba Esters, Niacinamide, PEG-16 Macadamia Glycerides, Cetearyl Alcohol, Glyceryl Stearate, Ceteareth-20, PEG-100 Stearate, Caprylic/Capric Triglyceride, Alcohol Denat., Palmitoyl Tripeptide-38, Caffeine, s-Mu-conotoxin CnIIIC Acetate, Copper Lysinate/Prolinate, Hydrolyzed Lupine Protein, Terminalia Ferdinandiana Fruit Extract, Methylglucoside Phosphate, Sodium Hyaluronate, Saccharomyces Cerevisiae Extract, Arginine, Glycine, Hydroxypropyl Cyclodextrin, Carbomer, Hexylene Glycol, Citric Acid, Sodium Hydroxide, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol

Source

Questions

What does the 80/100 score for our InterFuse Treatment Cream EYE build mean?

We split InterFuse Treatment Cream EYE into 6 standout parts worth 100 points in total. The build earns 80 of a possible 84. 84 is the most we claim, because some standouts have no close retail equivalent.

What is the best dupe for InterFuse Treatment Cream EYE?

Olay Brightening Eye Cream with Vitamin C (Vitamin C + Peptide 24 Eye Cream) by Olay is our closest single-product match at 29 out of 100 for ~$29.99 (0.5 oz). It shares Niacinamide, Vitamin C, Peptides.

How much can I save on InterFuse Treatment Cream EYE?

InterFuse Treatment Cream EYE costs ~$135 for 0.5 fl oz (15 ml). The closest dupe costs ~$29.99, a saving of about $105.01. Prices change, so check the seller page.

Is Olay Brightening Eye Cream with Vitamin C (Vitamin C + Peptide 24 Eye Cream) exactly the same as InterFuse Treatment Cream EYE?

No. Dupes share the key actives but can differ in concentration, vehicle and supporting ingredients. Missing from this one: Caffeine (not confirmed), Palmitoyl tripeptide-38, Conotoxin-like peptide. See our methodology for how we score.